2 Rheumatoid Arthritis Drugs Tied to Lower Risk of Parkinson’s

2 Rheumatoid Arthritis Medication Tied to Decrease Danger of Parkinson’s

By Robert Preidt
HealthDay Reporter

FRIDAY, Jan. 28, 2022 (HealthDay Information) — Two rheumatoid arthritis medicine present potential for reducing the danger of Parkinson’s illness, new analysis reveals.

Some earlier research have discovered that individuals with rheumatoid arthritis have a decrease danger of Parkinson’s, and it was recommended {that a} class of rheumatoid arthritis medicine known as disease-modifying antirheumatic medicine (DMARDs) could play a task in that decreased danger.

To be taught extra, researchers analyzed information from hundreds of sufferers in Finland.

The usage of most DMARDs — together with methotrexate, sulfasalazine, gold preparations or immunosuppressants — no less than three years earlier than Parkinson’s illness analysis was not related to the danger of the illness in these with rheumatoid arthritis, in accordance with the examine printed on-line Jan. 21 within the journal Neurology.

Nonetheless, the researchers did discover that rheumatoid arthritis sufferers who took the DMARDs chloroquine or hydroxychloroquine had a 26% decrease danger of Parkinson’s illness.

Each of those medicine have an effect on the immune system and have been proven to have anti-Parkinson’s potential in animal research, in accordance with the researchers. However outcomes of animal research are sometimes completely different from these in people.

The brand new examine was led by Anne Paakinaho of the Faculty of Pharmacy on the College of Jap Finland in Kuopio.

Her workforce known as for additional investigation of the medicine’ doable protecting results in opposition to Parkinson’s.

The examine — funded by the Michael J. Fox Basis for Parkinson’s Analysis — managed for size of time with rheumatoid arthritis, age, intercourse and different well being circumstances, similar to coronary heart illness and diabetes.

The danger components for Parkinson’s illness are unclear, the examine authors famous in a journal information launch.

Earlier research have linked rheumatoid arthritis with Parkinson’s. However they’ve yielded conflicting findings, with rheumatoid arthritis being related to both a decrease or greater danger of Parkinson’s.

Extra info

The Parkinson’s Basis has extra on Parkinson’s illness.

SOURCE: College of Jap Finland, information launch, Jan. 24, 2022

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