(HealthDay)—Acral lentiginous melanoma (ALM) survival varies in response to socioeconomic standing (SES) and race, with variations in SES contributing to survival disparities for Hispanic Black and White sufferers, in response to a examine printed within the February situation of the Journal of the American Academy of Dermatology.
Bernice Y. Yan, M.D., from the Donald and Barbara Zucker Faculty of Medication at Hofstra/Northwell in New Hyde Park, New York, and colleagues performed a retrospective cohort examine utilizing the Surveillance, Epidemiology, and Finish Outcomes database for 2000 to 2016 to match disease-specific survival in ALM throughout SES and race. A complete of two,245 sufferers had been recognized with a primary ALM prognosis.
The researchers discovered that the five-year disease-specific survival was 77.8%. In contrast with these within the highest SES quintile, sufferers within the lowest and second-to-lowest SES quintiles had 1.33 (95% confidence interval, 0.90 to 1.96) and 1.42 (95% confidence interval, 1.03 to 1.97) instances the danger for loss of life, respectively, after adjustment. The danger for loss of life was elevated 1.48 (95% confidence interval, 1.10 to 1.99) and 1.24 (95% confidence interval, 0.88 to 1.79) instances for Hispanic White and Black sufferers, respectively, versus non-Hispanic Whites. After adjustment for SES and American Joint Committee on Most cancers stage at prognosis, the hazard ratios for ALM-specific loss of life had been attenuated in Hispanic White and Black sufferers.
“Importantly, our examine means that SES partially contributes to elevated ALM mortality in Hispanic White and Black sufferers,” the authors write. “Additional investigations into elements accounting for SES and race disparities could enhance survival outcomes in ALM.”
Bernice Y. Yan et al, Survival variations in acral lentiginous melanoma in response to socioeconomic standing and race, Journal of the American Academy of Dermatology (2021). DOI: 10.1016/j.jaad.2021.07.049
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Acral lentiginous melanoma survival varies by race, socioeconomic standing (2022, February 15)
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